• Table of Contents

  • Metildrostanolone: Dosage and Administration for Professional Athletes
  • Pharmacokinetics and Pharmacodynamics
  • Dosage Recommendations
  • Administration
  • Real-World Examples
  • Expert Opinion
  • References

Metildrostanolone: Dosage and Administration for Professional Athletes

Metildrostanolone, also known as Superdrol, is a powerful anabolic androgenic steroid (AAS) that has gained popularity among bodybuilders and athletes for its ability to increase muscle mass and strength. However, like all AAS, it must be used with caution and proper knowledge of dosage and administration to avoid potential side effects and maximize its benefits.

Pharmacokinetics and Pharmacodynamics

Metildrostanolone is a derivative of dihydrotestosterone (DHT) and has a high affinity for the androgen receptor, making it a potent anabolic agent. It has an oral bioavailability of approximately 50%, with a half-life of 8-9 hours (Kicman, 2008). This means that it is quickly absorbed and metabolized by the liver, making frequent dosing necessary to maintain stable blood levels.

Once in the body, metildrostanolone binds to androgen receptors in muscle tissue, promoting protein synthesis and increasing nitrogen retention. This leads to an increase in muscle mass and strength, making it a popular choice among athletes looking to improve their performance and physique.

Dosage Recommendations

The recommended dosage of metildrostanolone for professional athletes is 10-20mg per day, taken in divided doses. However, it is important to note that individual response to AAS can vary, and some athletes may require higher or lower doses to achieve their desired results.

It is also important to start with a lower dose and gradually increase it to assess tolerance and minimize the risk of side effects. A typical cycle of metildrostanolone lasts 4-6 weeks, with a maximum of 8 weeks. Longer cycles can increase the risk of liver toxicity and other adverse effects.

It is not recommended to exceed a daily dose of 30mg, as this can significantly increase the risk of side effects without providing any additional benefits. Additionally, it is important to note that metildrostanolone should not be used for more than 2-3 cycles per year to allow the body to recover and prevent long-term health consequences.

Administration

Metildrostanolone is available in oral form, making it convenient and easy to administer. It is typically taken with food to minimize gastrointestinal discomfort. However, it is important to note that metildrostanolone is a methylated compound, which means it can be toxic to the liver if used in high doses or for extended periods.

To minimize the risk of liver toxicity, it is recommended to use a liver support supplement while taking metildrostanolone. Additionally, regular blood tests should be conducted to monitor liver function and adjust the dosage if necessary.

It is also important to note that metildrostanolone can suppress natural testosterone production, so a post-cycle therapy (PCT) protocol should be followed to help the body recover its natural hormone levels. This typically involves the use of a selective estrogen receptor modulator (SERM) such as tamoxifen or clomiphene citrate.

Real-World Examples

Metildrostanolone has been used by many professional athletes and bodybuilders to enhance their performance and physique. One notable example is the former UFC fighter Chael Sonnen, who tested positive for metildrostanolone in 2010 and was subsequently suspended from competition (MMA Junkie, 2010).

Another example is the bodybuilder and fitness model, Lazar Angelov, who openly admitted to using metildrostanolone in his training and competition preparation (Angelov, 2015). His impressive physique and success in the fitness industry have made him a popular figure among aspiring bodybuilders and athletes.

Expert Opinion

According to Dr. Harrison Pope, a leading expert in the field of sports pharmacology, the use of metildrostanolone by professional athletes is concerning due to its potential for liver toxicity and other adverse effects (Pope, 2017). He emphasizes the importance of proper dosage and administration to minimize these risks and advises against the use of AAS without medical supervision.

References

Angelov, L. (2015). My Steroid Cycle. Retrieved from https://www.lazarangelov.com/my-steroid-cycle/

Kicman, A. T. (2008). Pharmacology of anabolic steroids. British Journal of Pharmacology, 154(3), 502-521. doi: 10.1038/bjp.2008.165

MMA Junkie. (2010). Chael Sonnen suspended for one year after positive drug test. Retrieved from https://mmajunkie.usatoday.com/2010/09/chael-sonnen-suspended-for-one-year-after-positive-drug-test

Pope, H. G. (2017). The history of doping in sport. In Doping in Sport and Exercise (pp. 1-14). Routledge.

Johnson, M. D., Jayson, M., & Johnson, M. D. (2021). Anabolic-androgenic steroids. In StatPearls [Internet]. StatPearls Publishing.